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When the Arizona Cardinals match up with the Green Bay Packers at 4:25 p.m. ET on Sunday, Oct. 19, our projection system predicts the Cardinals will come out on top. Our model also projects the spead, point total, and final score, which you can check out below.
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Packers vs. Cardinals Game Info and TV Channel
- When: Sunday, October 19, 2025 at 4:25 p.m. ET
- Where: State Farm Stadium in Glendale, Arizona
- TV: FOX
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Listen to the game on 97.3 The Game
Packers vs. Cardinals Odds and Betting Info
- Spread favorite: Packers (-7)
- Moneyline: Packers (-355), Cardinals (+283)
- Total: 45 points
Packers vs. Cardinals Prediction
- Pick ATS: Cardinals (+7)
- Pick OU: Under (45)
Prediction:
Cardinals 23 - Packers 22
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Packers vs. Cardinals Betting Insights
- The Packers have covered twice in five chances against the spread this season.
- The Cardinals have won three games against the spread this year, failing to cover three times.
- Green Bay has been favored by 7 points or more this season twice, and failed to cover both times.
- Arizona has won its only game this season when playing as at least 7-point underdogs.
- This season, games featuring the Packers have hit the over twice.
- In the Cardinals' six contests this season, the combined scoring has gone over the point total three times.
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